Healthcare

How can we reliably dose medications across 5 days?

About 7%-14% of women have migraines only at the time of menstruation; these are called true menstrual migraines. Menstrual migraine attacks usually last longer than other migraine attacks, and short-term treatments do not work as well with menstrual migraines as they do with other kinds of migraines.

The frequency and severity of these attacks lead to a high disease burden and a significant decrease in life quality. These patients often use preventative medication on a five day regimen that begins 2 days before the menses. Each day, a non-steroidal anti-inflammatory drug (NSAID) is given in a regular dose as usually prescribed for moderate to severe pain. In addition at day 3, a deliberate Triptane (a serotonin receptor agonist drug) is given.

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Currently the appropriate NSAIDs and Triptane tablets must be taken separately on each of the five consecutive days of the preventive treatment. We’d like to develop a medical device for these patients that handles the dosing and timing. We expect that this device will offer our patients more freedom and will also help increase compliance with the medication schedule.

Your application technology should allow the application of an NSAID and a triptan over five days in timely manner. The patient should be able to initiate the total medication in one action. The less invasive the technology is, the better (injections should be avoided).

1. What kind of technology would you propose?
2. How is the medication applied?
3. Why do you think your proposed application technology will increase compliance for the patient (i.e. taking the right doses at the right times)?
4. Would your technology need a specific NSAID and/or Triptane drug? If so, why?

Use any charts, diagrams, images, sketches, or visuals to help communicate your idea.

Please note: your submission should not suggest a medication that can be taken orally

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